BRD4 promotes hepatic stellate cells activation and hepatic fibrosis via mediating P300/H3K27ac/PLK1 axis
Miao Cheng, Juanjuan Li, Juanjuan Li, Xue-ni Niu, Lin Zhu, Jinyu Liu, Pengcheng Jia, Sai Zhu, Hongwu Meng, Xiongwen Lv, Cheng Huang, Jun Li, Jun Li
Topics & Concepts
Hepatic stellate cellGene knockdownCancer researchCell biologyChemistryHepatic fibrosisMyofibroblastExtracellular matrixBRD4EpigeneticsFibrosisApoptosisBiologyPathologyMedicineBromodomainBiochemistryEndocrinologyGeneLiver physiology and pathologyProtein Degradation and InhibitorsCancer Mechanisms and Therapy