β-Cyclodextrin-Immobilized Ni/Graphene Electrode for Electrochemical Enantiorecognition of Phenylalanine
Feiyue Chen, Zhiqin Fan, Yangguang Zhu, Huifang Sun, Jinhong Yu, Nan Jiang, Shichao Zhao, Guosong Lai, Aimin Yu, Cheng‐Te Lin, Chen Ye, Li Fu
Abstract
In this work, a Ni/graphene (Ni/G) electrode was designed and fabricated by plasma-enhanced chemical vapor deposition (PECVD) for the ultrasensitive recognition of d- and l-phenylalanine. Through a single-step PECVD process, the Ni/G electrode can achieve better hydrophilicity and larger catalytic surface area, which is beneficial for the electrochemical recognition of bio-objects. After surface modification with β-cyclodextrin, the Ni/G electrode can distinguish d-phenylalanine from l-phenylalanine according to a 0.09 V peak shift in differential pulse voltammetry tests. Moreover, this Ni/G electrode achieved a detection limit as low as 1 nM and a wide linear range from 1 nM to 10 mM toward l-phenylalanine, with great storage stability and working stability.