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Modeling early gastrulation in human blastoids with DNA methylation patterns of natural blastocysts

Han Xie, Chenrui An, Bing Bai, Jiajia Luo, Nianqin Sun, Baiquan Ci, Long Jin, Phoenix K. H. Mo, Yawen Lu, Ke Zhong, Yang Yu, Tao Tan, Rong Li, Yong Fan

2025Cell stem cell21 citationsDOI

Topics & Concepts

BiologyDNA methylationGastrulationMethylationNatural (archaeology)Cell biologyBlastocystDNAEmbryoComputational biologyGeneticsEvolutionary biologyAndrologyGeneEmbryogenesisGene expressionPaleontologyMedicineEpigenetics and DNA MethylationPrenatal Screening and DiagnosticsRenal and related cancers