Formal nucleophilic pyrrolylmethylation<i>via</i>palladium-based auto-tandem catalysis: switchable regiodivergent synthesis and remote chirality transfer
Zhi Chen, Zhi Chen, Yufan Li, Shun‐Zhong Tan, Qin Ouyang, Zhichao Chen, Zhichao Chen, Wei Du, Ying‐Chun Chen
Abstract
-Pd(0) complexes between Pd(0) and chiral 1,3-diene intermediates in the key vinylogous addition step. A few control experiments were conducted to elucidate the palladium-involved tandem reaction and regiodivergent synthesis.
Topics & Concepts
PalladiumTandemChirality (physics)NucleophileCatalysisChemistryCombinatorial chemistryStereochemistryMaterials sciencePhysicsOrganic chemistryComposite materialChiral symmetry breakingQuantum mechanicsQuarkNambu–Jona-Lasinio modelCatalytic C–H Functionalization MethodsCatalytic Alkyne ReactionsAsymmetric Hydrogenation and Catalysis