Litcius/Paper detail

TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1

Jie Su, Sophie M. Morgani, Charles J. David, Qiong Wang, Ekrem Emrah Er, Yun-Han Huang, Harihar Basnet, Yilong Zou, Weiping Shu, Rajesh K. Soni, Ronald C. Hendrickson, Anna‐Katerina Hadjantonakis, Joan Massagué

2020Nature495 citationsDOIOpen Access PDF

Topics & Concepts

SMADBiologyCell biologyCancer researchTransforming growth factorTranscription factorSnailEpithelial–mesenchymal transitionMAPK/ERK pathwaySNAI1Signal transductionDownregulation and upregulationGeneGeneticsEcologyRenal and related cancersPancreatic and Hepatic Oncology ResearchLiver physiology and pathology