Internal probe-external recognition immunosensor fabricated on nanochannels for reagent-free electrochemical detection of interleukin-1β
Huanrui Wang, H. Wang, Fei Yan
Abstract
. The immunosensor was successfully applied to IL-1β detection in fetal bovine serum (FBS). By eliminating the need for additional signal probes, the developed immunosensor simplifies the detection process, demonstrates excellent anti-interference and stability, and offers a new approach for reagent-free biomarker detection in complex samples.
Topics & Concepts
Detection limitMaterials scienceNanotechnologyLinear rangeElectrodeElectrochemistrySIGNAL (programming language)BiosensorNanoparticleColloidal goldCovalent bondCarbon nanotubeNanometreMolecular recognitionImmunoassayGlassy carbonElectrochemical gas sensorComposite numberMesoporous materialChemistryWide dynamic rangeLayer (electronics)Nanopore and Nanochannel Transport StudiesAdvanced biosensing and bioanalysis techniquesElectrochemical Analysis and Applications