Directional conformer exchange in dihydrofolate reductase revealed by single-molecule nanopore recordings
Nicole Stéphanie Galenkamp, Annemie Biesemans, Giovanni Maglia
Topics & Concepts
Conformational isomerismDihydrofolate reductaseChemistryNanoporeAffinitiesStereochemistryMoleculeConformational changeLigand (biochemistry)Small moleculeCrystallographyEnzymeNanotechnologyBiochemistryReceptorOrganic chemistryMaterials scienceNanopore and Nanochannel Transport StudiesFuel Cells and Related MaterialsMembrane-based Ion Separation Techniques