Synthesis of new magnetic nanocatalyst Fe3O4@CPTMO-phenylalanine-Ni and its catalytic effect in the preparation of substituted pyrazoles
Samaneh Bikas, Ahmad Poursattar Marjani, Sepideh Bibak, Hamideh Sarreshtehdar Aslaheh
Abstract
Abstract In this study, a new, efficient and stable magnetically heterogeneous nanocatalyst of Fe 3 O 4 @CPTMO-phenylalanine-Ni via multi steps process starting from simple and cost-effective precursors was designed and successfully synthesized, and physico-chemical, structural, and magnetic properties have fully been characterized by several analytical methods involving SEM–EDS, FT-IR, TGA, VSM, XRD, ICP, BET, TEM, and EMA. The catalytic performance of the Fe 3 O 4 @CPTMO-phenylalanine-Ni can be used as an effective and recyclable nanocatalyst with facile separation by magnetic forces for the preparation of substituted pyrazoles with high yields through the one-pot, three-component condensation reaction of various arylglyoxals, diketones, and 1 H -pyrazole-5-amines under mild conditions. The nanocatalyst’s activity after being used by four consecutive times in a cycle reaction without distinct deterioration remained unchanged or was found to be a slight decrease. The advantages of this study are simplicity, low cost, facile synthesis process, and environmentally secure nature.