Prune supplementation for 12 months alters the gut microbiome in postmenopausal women
Abigayle M. R. Simpson, Mary Jane De Souza, Janhavi J Damani, Connie J. Rogers, Nancy I. Williams, Connie M. Weaver, Mário G. Ferruzzi, Sydney Corbin, Cindy H. Nakatsu
Abstract
= 0.002). Differing gut microbiomes and correlation of some taxa with select phenolic metabolites and inflammatory markers, particularly Lachnospiraceae, after prune consumption suggest a potential mechanism mediating health effects. The microbiome differences at each dose may have implications for the use of prunes as a non-pharmacological whole food intervention for gut health.
Topics & Concepts
LachnospiraceaeMicrobiomeBiology16S ribosomal RNAPhysiologyZoologyInternal medicineBacteriaMedicineFirmicutesBioinformaticsGeneticsGut microbiota and healthDiet and metabolism studiesPhytoestrogen effects and research