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Synthesis and Chiroptical Properties of Planar Chiral Azahelicenes Based on [2.2]Paracyclophane

Dan Xu, Wen‐Hua Zheng

2021Organic Letters19 citationsDOI

Abstract

Three pairs of planar chiral heteroarenes were synthesized using palladium-catalyzed Buchwald-Hartwig coupling and hypervalent iodine-mediated oxidative cyclization from optically pure 4-amino[2.2]paracyclophane. Among them, an enantiomer of planar chiral azahelicene was found to have circularly polarized luminescence activity that was remarkably stronger than that of planar chiral heteroarenes.

Topics & Concepts

Hypervalent moleculeChemistryPlanarEnantiomerOxidative coupling of methaneCombinatorial chemistryPlanar chiralityLuminescencePalladiumStereochemistryOptically activeEnantioselective synthesisCrystallographyIodineCatalysisOrganic chemistryMaterials scienceOptoelectronicsComputer graphics (images)Computer scienceSynthesis and Properties of Aromatic CompoundsLuminescence and Fluorescent MaterialsAdvanced NMR Techniques and Applications
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