Computational identification of potential chemoprophylactic agents according to dynamic behavior of peroxisome proliferator-activated receptor gamma
Zhiwei Yang, Yizhen Zhao, Dongxiao Hao, He Wang, Shengqing Li, Lintao Jia, Xiaohui Yuan, Lei Zhang, Lingjie Meng, Shengli Zhang
Abstract
. These results might aid the development of chemopreventive drugs, and the integrated VS strategy could be conducive to drug design for highly flexible biomacromolecules.
Topics & Concepts
Peroxisome proliferator-activated receptorIdentification (biology)PeroxisomeChemistryComputational biologyPharmacologyReceptorInternal medicineMedicineBiochemistryBiologyBotanyPeroxisome Proliferator-Activated ReceptorsReceptor Mechanisms and SignalingEicosanoids and Hypertension Pharmacology