Litcius/Paper detail

Accelerating aqueous electrolyte design with automated full-cell battery experimentation and Bayesian optimization

Jackie T. Yik, Carl Hvarfner, Jens Sjölund, Erik J. Berg, Leiting Zhang

2025Cell Reports Physical Science16 citationsDOIOpen Access PDF

Abstract

The integration of automation and data-driven methodologies offers a promising approach to accelerating materials discovery in energy storage research. Thus far, in battery research, coin-cell assembly has advanced to become nearly fully automated but remains largely disconnected from data-driven methods. To bridge the disconnect, this work presents a self-driving laboratory framework to accelerate electrolyte discovery by integrating automated coin-cell assembly, galvanostatic cycling of LiFePO 4 ||Li 4 Ti 5 O 12 organic-aqueous full cells, and Bayesian optimization for selecting subsequent experiments based on prior results. The study explored an organic-aqueous hybrid electrolyte system comprising four co-solvents and two lithium-conducting salts. Using this framework, cells with an optimized electrolyte cycled with at least 94% Coulombic efficiency. Additionally, online electrochemical mass spectrometry revealed that the optimized organic co-solvents successfully mitigated the parasitic hydrogen evolution reaction. The results highlight the potential of combining Bayesian optimization with autonomous full-cell experimentation while contributing new electrolyte design insights for next-generation aqueous batteries. • Stationary robotic platform, ODACell 2, combines battery testing and machine learning • Optimized electrolytes are dimethyl sulfoxide and trimethyl phosphate based • Data-driven insight suggests optimized electrolytes deviate from monosolvent systems • Operando gas analysis of optimized electrolytes shows suppressed hydrogen evolution A stationary robotic platform, ODACell 2, presents a self-driving lab framework combining Bayesian optimization with automated battery assembly, cycling, and liquid handling. It demonstrates the discovery of high-performance organic-aqueous hybrid electrolytes, achieving >94% Coulombic efficiency in full-cell cycling. Operando gas analysis shows mitigated hydrogen evolution in optimized electrolytes.

Topics & Concepts

ElectrolyteBattery (electricity)Bayesian optimizationComputer scienceBayesian probabilityAqueous solutionChemistryArtificial intelligenceElectrodePhysicsThermodynamicsOrganic chemistryPower (physics)Physical chemistryAdvanced Battery Technologies ResearchAdvanced Battery Materials and TechnologiesAdvanced battery technologies research