Melatonin ameliorates nickel induced autophagy in mouse brain: Diminution of oxidative stress
Senqiu Qiao, Yue Sun, Yangyang Jiang, Xiaoming Chen, Jingzeng Cai, Qi Liu, Ziwei Zhang
Topics & Concepts
Oxidative stressNeurotoxicityAutophagyPI3K/AKT/mTOR pathwayMelatoninReactive oxygen speciesProtein kinase BLY294002ChemistryPhosphatidylinositolAntioxidantPharmacologyEndocrinologyInternal medicineBiologyBiochemistryToxicityKinaseSignal transductionMedicineApoptosisAutophagy in Disease and TherapyHeavy Metal Exposure and ToxicityHydrogen's biological and therapeutic effects