Computed tomography for myocardial characterization in ischemic heart disease: a state-of-the-art review
Marly van Assen, Marleen Vonder, Gert Jan Pelgrim, Philipp L. von Knebel Doeberitz, Rozemarijn Vliegenthart
Abstract
This review provides an overview of the currently available computed tomography (CT) techniques for myocardial tissue characterization in ischemic heart disease, including CT perfusion and late iodine enhancement. CT myocardial perfusion imaging can be performed with static and dynamic protocols for the detection of ischemia and infarction using either single- or dual-energy CT modes. Late iodine enhancement may be used for the analysis of myocardial infarction. The accuracy of these CT techniques is highly dependent on the imaging protocol, including acquisition timing and contrast administration. Additionally, the options for qualitative and quantitative analysis and the accuracy of each technique are discussed.