Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by <sup>19</sup>F NMR Spectroscopy
José Daniel Martínez, Ana I. Manzano, Eva Calviño, Ana de Diego, Borja Rodríguez de Francisco, Cecilia Romanò, Stefan Oscarson, Óscar Millet, Hans‐Joachim Gabius, Jesús Jiménez‐Barbero, F. Javier Cañada
Abstract
, it became possible to simultaneously define their monosaccharide selectivity and identify the essential hydroxyls for interaction.
Topics & Concepts
ChemistryMonosaccharideGalactoseLectinCarbohydrateNuclear magnetic resonance spectroscopyAnomerMannoseStereochemistryOrganic chemistryBiochemistryGlycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisProteoglycans and glycosaminoglycans research