NF-κB mediates lipopolysaccharide-induced alternative pre-mRNA splicing of MyD88 in mouse macrophages
Frank Fang-Yao Lee, Kevin Davidson, Chelsea Harris, Jazalle McClendon, William J. Janssen, Scott Alper
Abstract
may provide a sensitive mechanism that ensures robust termination of inflammation for tissue repair and restoration of normal tissue homeostasis once an infection is controlled.
Topics & Concepts
LipopolysaccharideRNA splicingNF-κBChemistryMessenger RNAAlternative splicingMolecular biologyCell biologyBiologyGeneBiochemistryImmunologySignal transductionRNARNA Research and SplicingImmune Response and InflammationNF-κB Signaling Pathways