Litcius/Paper detail

Hydrogels in drug delivery: Progress and challenges

Todd Hoare, Daniel S. Kohane

2008Polymer3,707 citationsDOIOpen Access PDF

Abstract

There has been considerable progress in recent years in addressing the clinical and pharmacological limitations of hydrogels for drug delivery applications but substantial challenges remain. Here we discuss recent progress in overcoming these challenges, particularly with regards to effectively delivering hydrogels inside the body without implantation, prolonging the release kinetics of drugs from hydrogels, and expanding the nature of drugs which can be delivered using hydrogel-based approaches.

Topics & Concepts

Self-healing hydrogelsDrug deliveryNanotechnologyDrugMaterials scienceMedicinePharmacologyPolymer chemistryHydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems3D Printing in Biomedical Research