Engineered pegRNAs improve prime editing efficiency
James W. Nelson, Peyton B. Randolph, Simon P. Shen, Kelcee A. Everette, Peter J. Chen, Andrew V. Anzalone, Meirui An, Gregory A. Newby, Jonathan C. Chen, Alvin Hsu, David Liu
Topics & Concepts
Prime (order theory)Genome editingComputer scienceComputational biologyChemistryBiologyBiochemistryMathematicsCRISPRCombinatoricsGeneCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanisms