Construction of paclitaxel-based antibody–drug conjugates with a PEGylated linker to achieve superior therapeutic index
Ting Shao, Tianzhi Chen, Yuning Chen, Xiaoyue Liu, Yili Chen, Qi Wang, Tong Zhu, Maojun Guo, Hui Li, Dianwen Ju, Chunhe Wang
Topics & Concepts
PaclitaxelLinkerConjugateTherapeutic indexDrugPharmacologyMedicineIndex (typography)AntibodyMonoclonal antibodyImmunologyComputer scienceSurgeryChemotherapyMathematicsWorld Wide WebOperating systemMathematical analysisHER2/EGFR in Cancer ResearchMonoclonal and Polyclonal Antibodies ResearchCancer Treatment and Pharmacology