DDTC-Cu(I) based metal-organic framework (MOF) for targeted melanoma therapy by inducing SLC7A11/GPX4-mediated ferroptosis
Chan Li, Sheng Zhou, Chuncheng Chen, Lijun Zhu, Shijie Li, Zhuoyue Song, Jian Liang, Chunzhi Tang, Nenggui Xu, Tao Liu, Shihui Liu
Topics & Concepts
ChemistryDisulfiramIn vivoDithiocarbamateCisplatinMetal-organic frameworkPharmacologyCancer researchCombinatorial chemistryBiochemistryOrganic chemistryChemotherapyBiotechnologyMedicineAdsorptionSurgeryBiologyFerroptosis and cancer prognosisPeptidase Inhibition and AnalysisCancer Mechanisms and Therapy