Illuminating the Role of Vitamin A in Skin Innate Immunity and the Skin Microbiome: A Narrative Review
Fritzlaine C. Roche, Tamia Harris-Tryon
Abstract
Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficiencies in Vitamin A have been linked to impaired immune response and increased susceptibility to skin infections and inflammatory skin disease. This narrative review summarizes recent primary evidence that elucidates the role of vitamin A and its derivatives on innate immune regulators through mechanisms that promote skin immunity and sustain the skin microbiome.
Topics & Concepts
MicrobiomeInnate immune systemImmunityImmune systemImmunologyBiologyVitamin D and neurologyVitaminInflammationMedicineBioinformaticsEndocrinologyDermatology and Skin DiseasesAcne and Rosacea Treatments and EffectsPsoriasis: Treatment and Pathogenesis