Geniposide protects against neurotoxicity in mouse models of rotenone-induced Parkinson's disease involving the mTOR and Nrf2 pathways
Qian Zhou, Bin Chen, Yijiao Xu, Yue Wang, Ziheng He, Xueting Cai, Yu Qin, Juan Ye, Yang Yang, Jianping Shen, Peng Cao
Topics & Concepts
RotenoneNeuroprotectionNeurodegenerationNeurotoxicityPharmacologyOxidative stressPI3K/AKT/mTOR pathwayDopaminergicChemistryParkinson's diseaseDopamineApoptosisMedicineBiochemistryToxicityMitochondrionInternal medicineOrganic chemistryDiseaseSaffron Plant Research StudiesParkinson's Disease Mechanisms and TreatmentsNeurological Disease Mechanisms and Treatments