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Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy

Yuanyuan Liu, Meng Zheng, Mingzhu Jiao, Chengnan Yan, Sen Xu, Qiuli Du, Marco Morsch, Jinlong Yin, Bingyang Shi

2021Biomaterials65 citationsDOI

Topics & Concepts

PTENmicroRNACancer researchAngiogenesisMaterials scienceCarcinogenesisBlood–brain barrierProtein kinase BTargeted therapyBrain tumorGlioblastomaU87GliomaPI3K/AKT/mTOR pathwayCancerMedicineSignal transductionChemistryBiologyCell biologyInternal medicinePathologyBiochemistryGeneCentral nervous systemMicroRNA in disease regulationAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery
Polymeric nanoparticle mediated inhibition of miR-21 with enhanced miR-124 expression for combinatorial glioblastoma therapy | Litcius