J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum
Philipp Nitschke, Samantha Lodge, Torben Kimhofer, Reika Masuda, Sze-How Bong, Drew A. Hall, Hartmut Schäfer, Manfred Spraul, Nils Pompe, Tammo Diercks, Ganeko Bernardo‐Seisdedos, José M. Mato, Óscar Millet, Daniella Susic, Amanda Henry, Emad El‐Omar, Elaine Holmes, John C. Lindon, Jeremy K. Nicholson, Julien Wist
Abstract
= 631). The data show that JEDI is an improved approach to selectively investigate inflammatory signals in serum and may have widespread diagnostic applicability to disease states associated with systemic inflammation.
Topics & Concepts
ChemistryInflammationPhospholipidNuclear magnetic resonanceSupramolecular chemistryProton NMRNuclear magnetic resonance spectroscopyGlycoproteinProtonPulse sequenceMoleculeBiochemistryBiophysicsStereochemistryInternal medicineOrganic chemistryQuantum mechanicsPhysicsMembraneBiologyMedicineMetabolomics and Mass Spectrometry StudiesLiver Disease Diagnosis and TreatmentNMR spectroscopy and applications