A One Health Genomic Investigation of Gentamicin Resistance in Escherichia coli from Human and Chicken Sources in Canada, 2014 to 2017
Graham W. Cox, Brent P. Avery, E. Jane Parmley, Rebecca Irwin, Richard J. Reid‐Smith, Anne Deckert, Rita Finley, Danielle Daignault, George G. Zhanel, Michael R. Mulvey, Amrita Bharat
Abstract
We investigated whether gentamicin resistance (Gen r ) in Escherichia coli isolates from human infections was related to Gen r E. coli in chicken and whether resistance may be due to coselection from use of lincomycin-spectinomycin in chickens on farms. Whole-genome sequencing was performed on 483 Gen r E. coli isolates isolated between 2014 and 2017.
Topics & Concepts
GentamicinEscherichia coliMicrobiologyAntibiotic resistanceBiologyEnterobacteriaceaeAntibioticsBiotechnologyGeneticsGeneAntibiotic Resistance in BacteriaEscherichia coli research studiesEnterobacteriaceae and Cronobacter Research