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Isobavachalcone prevents osteoporosis by suppressing activation of ERK and NF-κB pathways and M1 polarization of macrophages

Xiangyu Wang, Quanbo Ji, Wenhao Hu, Zhifa Zhang, Fanqi Hu, Shiqi Cao, Qi Wang, Yongyu Hao, Meng Gao, Xuesong Zhang

2021International Immunopharmacology34 citationsDOI

Topics & Concepts

RANKLOsteoclastMAPK/ERK pathwayNF-κBChemistryCell biologyOvariectomized ratSignal transductionReceptorActivator (genetics)Estrogen receptorIκBαCancer researchPharmacologyInternal medicineEndocrinologyBiologyMedicineBiochemistryHormoneBreast cancerCancerBone Metabolism and DiseasesNF-κB Signaling PathwaysEstrogen and related hormone effects
Isobavachalcone prevents osteoporosis by suppressing activation of ERK and NF-κB pathways and M1 polarization of macrophages | Litcius