Litcius/Paper detail

Edge Removal and <i>Q</i>-Learning for Stabilizability of Boolean Networks

Wenrong Li, Haitao Li

2023IEEE Transactions on Neural Networks and Learning Systems15 citationsDOI

Abstract

This article develops a new edge removal mechanism for the global stabilizability of Boolean networks (BNs). In order to achieve the edge removal control, several control variables are properly placed into the dynamics of BNs based on the fundamental logical operators. On the basis of the new edge removal mechanism, several necessary and sufficient conditions are obtained for the global stabilizability and set stabilizability of BNs. Furthermore, a kind of stable edge removal control is proposed and achieved via the -learning algorithm to optimize the edge removal mechanism. As an application, the edge removal control is used to verify whether or not the mammalian cortical area development model can be made stabilizable to the expected stable states.

Topics & Concepts

Enhanced Data Rates for GSM EvolutionControl (management)Mechanism (biology)Set (abstract data type)MathematicsBasis (linear algebra)Computer scienceArtificial intelligenceGeometryEpistemologyProgramming languagePhilosophyGene Regulatory Network AnalysisReceptor Mechanisms and Signaling3D Printing in Biomedical Research