Chromosomally and Plasmid-Located <i>mcr</i> in Salmonella from Animals and Food Products in China
Cai-Yue Mei, Yue Jiang, Qin-Chun Ma, Meng-Jun Lu, Han Wu, Zhenyu Wang, Xinan Jiao, Jing Wang
Abstract
Colistin is a last-resort antibiotic for severe infections caused by multidrug-resistant (MDR) Gram-negative pathogens. Colistin resistance genes mcr , particularly mcr-1 , have been found in Enterobacteriaceae around the world, mainly in Escherichia coli and Salmonella . Salmonella enterica is a major foodborne pathogen, with MDR Salmonella being considered a “Serious Threat Level pathogen” by the Centers for Disease Control and Prevention.
Topics & Concepts
MCR-1PlasmidSalmonella entericaBiologyColistinSalmonellaMicrobiologyGeneGeneticsEnterobacteriaceaeEscherichia coliAntimicrobialBacteriaAntibiotic Resistance in BacteriaSalmonella and Campylobacter epidemiologyPharmaceutical and Antibiotic Environmental Impacts