Regulation of <scp> pro‐σ <sup>K</sup> </scp> activation: a key checkpoint in <i>Bacillus subtilis</i> sporulation
Gaohui Sun, Moua Yang, Longguang Jiang, Mingdong Huang
Abstract
Summary The Gram‐positive bacterium Bacillus subtilis initiates the sporulation process under conditions of nutrient limitation. Here, we review related work in this field, focusing on the protein processing of the pro‐σ K activation. The purpose of this review is to illustrate the mechanism of pro‐σ K activation and provide structural insights into the regulation of spore production. Sporulation is not only important in basic science but also provides mechanistic insight for bacterial control in applications in, e.g., food industry.
Topics & Concepts
Bacillus subtilisBiologySporeKey (lock)MicrobiologyBacteriaCell biologyComputational biologyGeneticsEcologyBacterial Genetics and BiotechnologyBacteriophages and microbial interactionsEnzyme Structure and Function