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Adolescent Alcohol Use Trajectories: Risk Factors and Adult Outcomes

Wing See Yuen, Gary Chan, Raimondo Bruno, Philip Clare, Richard P. Mattick, Alexandra Aiken, Veronica Boland, Nyanda McBride, Jim McCambridge, Tim Slade, Kypros Kypri, L. John Horwood, Delyse Hutchinson, Jake M. Najman, Clara De Torres, Amy Peacock

2020PEDIATRICS118 citationsDOIOpen Access PDF

Abstract

OBJECTIVES: Adolescents often display heterogenous trajectories of alcohol use. Initiation and escalation of drinking may be important predictors of later harms, including alcohol use disorder (AUD). Previous conceptualizations of these trajectories lacked adjustment for known confounders of adolescent drinking, which we aimed to address by modeling dynamic changes in drinking throughout adolescence while adjusting for covariates. METHODS: = 1813) were used to model latent class alcohol use trajectories over 5 annual follow-ups (mean age = 13.9 until 17.8 years). Regression models were used to determine whether child, parent, and peer factors at baseline (mean age = 12.9 years) predicted trajectory membership and whether trajectories predicted self-reported symptoms of AUD at the final follow-up (mean age = 18.8 years). RESULTS: = 295). Having more alcohol-specific household rules reduced risk of early-onset heavy drinking compared with late-onset moderate drinking (relative risk ratio: 0.31; 99.5% confidence interval [CI]: 0.11-0.83), whereas having more substance-using peers increased this risk (relative risk ratio: 3.43; 99.5% CI: 2.10-5.62). Early-onset heavy drinking increased odds of meeting criteria for AUD in early adulthood (odds ratio: 7.68; 99.5% CI: 2.41-24.47). CONCLUSIONS: Our study provides evidence that parenting factors and peer influences in early adolescence should be considered to reduce risk of later alcohol-related harm. Early initiation and heavy alcohol use throughout adolescence are associated with increased risk of alcohol-related harm compared with recommended maximum levels of consumption (late-onset, moderate drinking).

Topics & Concepts

MedicineOdds ratioConfoundingDemographyConfidence intervalAlcohol use disorderInjury preventionPoison controlRelative riskCohort studyYoung adultAlcoholOddsLongitudinal studyLogistic regressionEnvironmental healthGerontologyInternal medicinePathologyBiochemistryChemistrySociologySubstance Abuse Treatment and OutcomesPrenatal Substance Exposure EffectsChild Abuse and Trauma