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<i>Bifidobacterium animalis</i> subsp. <i>lactis</i> A6 attenuates hippocampal damage and memory impairments in an ADHD rat model

Xindi Yin, Weichen Liu, Haihong Feng, Jiaqiang Huang, Qi Wang, Qi Zhang, Jingjing He, Ran Wang

2024Food & Function21 citationsDOI

Abstract

negatively associated with neurotransmitter release and anti-inflammatory effects in SHRs. Together, these results suggested that BAA6 improved memory function by ameliorating hippocampal damage, abnormal neurotransmitter release and cerebral inflammation by reshaping the gut microbiota in SHRs. This study provides a scientific basis for the development and application of BAA6 as a promising dietary intervention to reduce the risk of ADHD.

Topics & Concepts

DopamineNeurotransmitterHippocampal formationPharmacologyGlutamate receptorProbioticGut floraLactobacillusBiologyInternal medicineEndocrinologyBiochemistryMedicineCentral nervous systemBacteriaReceptorGeneticsFermentationTryptophan and brain disordersAlzheimer's disease research and treatmentsStress Responses and Cortisol
<i>Bifidobacterium animalis</i> subsp. <i>lactis</i> A6 attenuates hippocampal damage and memory impairments in an ADHD rat model | Litcius