Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
Sung‐Hoon Kim, Jung‐Hyun Choi, Peng Wang, Christopher D. Go, Geoffrey G. Hesketh, Anne‐Claude Gingras, Seyed Mehdi Jafarnejad, Nahum Sonenberg
Topics & Concepts
mTORC1BiologyGTPaseCell biologyThreonineTransfer RNAGTP'Amino acidBiochemistryCytoplasmMitochondrionSignal transductionPhosphorylationEnzymeGeneSerineRNAPI3K/AKT/mTOR pathwayPI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanismsRNA Research and Splicing