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The m6A methyltransferase METTL3 promotes hypoxic pulmonary arterial hypertension

Yuhan Qin, Yong Qiao, Linqing Li, Erfei Luo, Dong Wang, Yuyu Yao, Chengchun Tang, Gaoliang Yan

2021Life Sciences98 citationsDOI

Topics & Concepts

PTENDownregulation and upregulationPI3K/AKT/mTOR pathwayCancer researchMessenger RNAProtein kinase BGene knockdownBiologyHypoxia (environmental)Cell biologyApoptosisSignal transductionChemistryGeneOxygenOrganic chemistryBiochemistryRNA modifications and cancerUbiquitin and proteasome pathwaysATP Synthase and ATPases Research
The m6A methyltransferase METTL3 promotes hypoxic pulmonary arterial hypertension | Litcius