Shikonin N-benzyl matrinic acid ester derivatives as novel telomerase inhibitors with potent activity against lung cancer cell lines
Hongwei Han, Cong He, Xingyu Chen, Yuelin Luo, Minkai Yang, Zhongling Wen, Jiabao Hu, Faxiang Lin, Mi Ra Han, Tongming Yin, Rongwu Yang, Hongyan Lin, Jinliang Qi, Yonghua Yang
Topics & Concepts
TelomeraseChemistryApoptosisCytotoxicityCell cultureCell growthCell cycle checkpointCancer cellTelomerase reverse transcriptaseCell cycleCancer researchMolecular biologyCancerBiochemistryIn vitroBiologyGeneGeneticsBioactive Compounds and Antitumor AgentsSynthesis of Organic CompoundsBioactive natural compounds