A Bio-inspired Multifunctionalized Silk Fibroin
Sofia Santi, Ines Mancini, Sandra Dirè, Emanuela Callone, G. Speranza, Nicola M. Pugno, Claudio Migliaresi, Antonella Motta
Abstract
favorable bioresponse, and moreover can be functionalized with different methods. The chemical structure of BMS was analyzed by using X-ray photoelectron spectroscopy, attenuated total reflection-Fourier transform infrared, cross-polarization magic angle spinning nuclear magnetic resonance techniques, and colorimetric assay. The SF and BMS solutions were cross-linked by sonication to form hydrogels or casted to make films in order to evaluate and compare the early adhesion and viability of MRC5 cells. BMS hydrogels were also characterized by rheological and thermal analyses.
Topics & Concepts
FibroinMaterials scienceSILKNanotechnologySericinPolymer scienceComposite materialSilk-based biomaterials and applicationsAntimicrobial Peptides and ActivitiesElectrospun Nanofibers in Biomedical Applications