Validation of the Corona-Score for rapid identification of SARS-CoV-2 infections in patients seeking emergency department care in the United States
Giuseppe Lippi, Brandon Michael Henry, Jonathan Hoehn, Stefanie W. Benoit, Justin L. Benoit
Abstract
To the editor, The diagnosis of coronavirus disease 2019 (COVID-19) is still straightforwardly based on the identification of severe acute respiratory disease coronavirus 2 (SARS-CoV-2) RNA in upper or lower respiratory tracts specimens by means of nucleic acid amplification tests (NAATs) Nonetheless, these techniques have some important drawbacks, such as the relatively low diagnostic sensitivity in nasopharyngeal swabs (i.e., typically lower than 80%) [2], the need of dedicated instrumentation and specialized personnel, as well as the relatively low throughput, which represent clear obstacles for purposes of large population screening
Topics & Concepts
Nucleic Acid Amplification TestsMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Emergency departmentIntensive care medicineCoronavirusPopulationIdentification (biology)DiseaseVirologyEmergency medicineMedical emergencyInternal medicineInfectious disease (medical specialty)BiologyEnvironmental healthChlamydia trachomatisPsychiatryBotanySARS-CoV-2 detection and testingRespiratory viral infections researchViral gastroenteritis research and epidemiology