Simvastatin mitigates depressive-like behavior in ovariectomized rats: Possible role of NLRP3 inflammasome and estrogen receptors’ modulation
Esther T. Menze, Hager Ezzat, Salma Ahmed Shawky, Marwa Sami, Eman H. Selim, Samar Ahmed, Nouran Maged, Nancy Nadeem, Shorouk Eldash, Haidy E. Michel
Topics & Concepts
Ovariectomized ratEndocrinologyInternal medicineEstrogen receptorEstrogenNeuroprotectionTLR4SimvastatinMedicinePhytoestrogensHormone replacement therapy (female-to-male)ReceptorHippocampal formationTamoxifenTLR2Selective estrogen receptor modulatorCancerBreast cancerTestosterone (patch)Endometriosis Research and TreatmentTryptophan and brain disordersStress Responses and Cortisol