Engineered PD-1/TIGIT dual-activating cell-membrane nanoparticles with dexamethasone act synergistically to shape the effector T cell/Treg balance and alleviate systemic lupus erythematosus
Qianqian Guo, Chuanrong Chen, Zhihua Wu, Wei Zhang, Liting Wang, Jian Yu, Longxia Li, Jiali Zhang, Yourong Duan
Topics & Concepts
TIGITImmune systemImmunologyProinflammatory cytokineCancer researchDownregulation and upregulationT cellMedicineChemistryInflammationBiochemistryGeneImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses