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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

Daniel W Lee, James N. Kochenderfer, Maryalice Stetler‐Stevenson, Yongzhi Cui, Cindy Delbrook, Steven A. Feldman, Terry J. Fry, Rimas J. Orentas, Marianna Sabatino, Nirali N. Shah, Seth M. Steinberg, D. Stroncek, Nick Tschernia, Constance M. Yuan, Hua Zhang, Ling Zhang, Steven A. Rosenberg, Alan S. Wayne, Crystal L. Mackall

2014The Lancet2,939 citationsDOI

Topics & Concepts

MedicineFludarabineChimeric antigen receptorCyclophosphamideInternal medicineRegimenCD19AntigenImmunologyGastroenterologyOncologyT cellChemotherapyImmune systemCAR-T cell therapy researchAcute Lymphoblastic Leukemia researchCutaneous lymphoproliferative disorders research
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial | Litcius