Structural insights into small-molecule KRAS inhibitors for targeting KRAS mutant cancers
Divya Pandey, Subhash C. Chauhan, Vivek K. Kashyap, Kuldeep K. Roy
Topics & Concepts
KRASViral OncogeneMutantGene isoformCancer researchOncogeneCell growthChemistrySmall moleculeMutationComputational biologyCancerBiologyCell biologyGeneticsCell cycleBiochemistryGeneProtein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerMelanoma and MAPK Pathways