The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes
Hejun Hu, Jingting Qiao, F.Q. Liu, Jinbao Wang, Shuo Sha, Qin He, Chen Cui, Jie Song, Nan Zang, L.S. Wang, Zheng Sun, L. Chen, Xinguo Hou
Topics & Concepts
IRF3LipotoxicityStingEndocrinologyInternal medicinePancreatic isletsSignal transductionBiologyCancer researchInflammationDownregulation and upregulationCell biologyInsulin resistanceMedicineInsulinIsletInnate immune systemReceptorBiochemistryAerospace engineeringEngineeringGeneinterferon and immune responsesRNA modifications and cancerInflammasome and immune disorders