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Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PDL1 within lipid nanoparticles

Yang Liu, Jun Li, Baowen Zhang, Shanshan Chen, Yanqiong Shen, Zhibin Li, Jiachen Zhang, Yi Yang, Min Li, Yucai Wang

2025Nature Biomedical Engineering39 citationsDOI

Topics & Concepts

In vivoAntigenMessenger RNAChemistryCell biologyBiologyMolecular biologyComputational biologyImmunologyGeneBiochemistryGeneticsRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research
Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PDL1 within lipid nanoparticles | Litcius