A label-free fluorescent biosensor for amplified detection of T4 polynucleotide kinase activity based on rolling circle amplification and catalytic hairpin assembly
Wanling Cui, Xiaoyang Fan, Wenqi Zhao, Jinrong Liu, Liangjie Zheng, Libing Zhou, Junye Zhang, Xiumei Zhang, Xiaoxin Wang
Topics & Concepts
Rolling circle replicationPrimer (cosmetics)BiosensorFluorescenceBiophysicsDNAChemistryCombinatorial chemistryPhosphodiester bondPolynucleotideBiochemistryBiologyDNA polymeraseRNAGeneOrganic chemistryPhysicsQuantum mechanicsAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery