Litcius/Paper detail

Central retinal vein occlusion after mRNA SARS-CoV-2 vaccination: A case report

Beatriz Endo, Silvana Bahamon, Dayron Fernando Martínez-Pulgarín

2021Indian Journal of Ophthalmology61 citationsDOIOpen Access PDF

Abstract

A central retinal vein occlusion (CRVO) case in a patient developed with sudden blurred vision in some hemifield areas of his left eye, maintaining 20/20 vision 15-days after the COVID-19 vaccination. Initial retinal findings were venous dilation and tortuosity with dispersing dot hemorrhages. Fluorescein angiography (FA) and optical coherence tomography (OCT) confirmed a non-ischemic CRVO diagnosis, and a complete blood panel was requested with average results. An intravitreal steroid dose was applied. A decrease in best-corrected visual acuity (BCVA) (20/30) with more intraretinal hemorrhages was documented. An intravitreal dose of bevacizumab and oral apixaban were added with a final BCVA of 20/20 with decreased hemorrhages. There is no specific causal relationship between COVID-19 vaccines and CRVO. Without previous risk factors and positive treatment response, this case may correlate the first COVID-19 vaccine dose and the event.

Topics & Concepts

MedicineCentral retinal vein occlusionOphthalmologyVisual acuityFluorescein angiographyBlurred visionCoronavirus disease 2019 (COVID-19)OcclusionCentral retinal veinRetinalOptical coherence tomographyMacular edemaSurgeryInternal medicineDiseaseInfectious disease (medical specialty)Retinal and Optic ConditionsSARS-CoV-2 and COVID-19 ResearchOcular Diseases and Behçet’s Syndrome