Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction
Qingwen Xiao, Bingling Zhong, Ying Hou, Miaojuan Wang, Baojian Guo, Ligen Lin, Yinning Zhou, Xiuping Chen
Topics & Concepts
Mitochondrial permeability transition poreReactive oxygen speciesCancer cellApoptosisNecrosisProgrammed cell deathOxidative stressMitochondrial ROSMitochondrionCancer researchChemistryCell biologyBiologyCancerBiochemistryGeneticsCell death mechanisms and regulationAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolism