Facile multifunctional IOL surface modification <i>via</i> poly(PEGMA-<i>co</i>-GMA) grafting for posterior capsular opacification inhibition
Jiayi Xia, Duoduo Lu, Yuemei Han, Jiahao Wang, Yueze Hong, Peiyi Zhao, Qiuna Fang, Quankui Lin
Abstract
ocular implantation was carried out on rabbit eyes to evaluate the effect of the coating modified IOL on the inhibition of postoperative PCO. It followed that such multifunctional coating modification can effectively inhibit the adhesion and proliferation of LECs and significantly reduce the incidence of PCO. All these results reveal that such PPG copolymer modification provides a facile yet effective way to inhibit PCO formation after IOL implantation.
Topics & Concepts
GraftingSurface modificationPolymer chemistryMaterials scienceChemistryChemical engineeringEngineeringComposite materialPolymerPhysical chemistryIntraocular Surgery and LensesAnesthesia and Pain ManagementRetinal and Macular Surgery