Zeolitic imidazolate framework-based nanoparticles for the cascade enhancement of cancer chemodynamic therapy by targeting glutamine metabolism
Hui Jian, Yun Zhang, Junyue Wang, Zhenxiang Chen, Tingyi Wen
Abstract
assessments further confirm the enhanced anticancer performance and good biocompatibility of ZIF(Fe)&CB nanoparticles. This study provides a promising strategy for the development and improvement of ROS-based anticancer nanosystems.
Topics & Concepts
GlutaminolysisGlutamineCancer cellChemistryReactive oxygen speciesBiochemistryDNA damageCancer researchCancerAmino acidBiologyDNAGeneticsNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation