TMEM106B-mediated SARS-CoV-2 infection allows for robust ACE2-independent infection in vitro but not in vivo
Kexin Yan, Troy Dumenil, Romal Stewart, Cameron R. Bishop, Bing Tang, Wilson Nguyen, Andreas Suhrbier, Daniel J. Rawle
Abstract
is likely an in vitro phenomenon with no apparent implications for infection in vivo.
Topics & Concepts
In vivoVirologyIn vitroSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BiologyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakMicrobiologyMedicineOutbreakInfectious disease (medical specialty)GeneticsPathologyDiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19