Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology
Takumi Ito, Yuki Yamaguchi, Hiroshi Handa
Topics & Concepts
CereblonUbiquitin ligaseUbiquitin-Protein LigasesUbiquitinCullinChemistryChemical biologyDDB1Cell biologyComputational biologyDegronBiologyBiochemistryGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsHistone Deacetylase Inhibitors Research