Chiral Recognition of In Situ-Oxidized Phosphine Oxides with Octahedral Indium Complexes by <sup>31</sup>P NMR Spectroscopy
Eun-Jeong Kwahk, Sumin Jang, Hyunwoo Kim
Abstract
Herein, efficient chiral recognition of phosphine oxides with octahedral indium complexes was demonstrated. Direct chiral analysis of in situ-prepared phosphine oxides formed using phosphines and hydrogen peroxide was conducted effectively via 31P nuclear magnetic resonance spectroscopy. Sufficient peak resolution of chiral phosphines was obtained consistently, thereby enabling the reliable determination of absolute chirality. Rational 1:1 binding models based on experiments and density functional theory calculations have been proposed.
Topics & Concepts
ChemistryPhosphineOctahedronChirality (physics)IndiumSpectroscopyNuclear magnetic resonance spectroscopyDensity functional theoryHydrogen peroxideIn situCrystallographyPhysical chemistryComputational chemistryCatalysisStereochemistryOrganic chemistryCrystal structureNambu–Jona-Lasinio modelPhysicsQuantum mechanicsQuarkChiral symmetry breakingMolecular spectroscopy and chiralityAnalytical Chemistry and ChromatographyAsymmetric Synthesis and Catalysis